Integrin alphaV, beta5

• NCBI Gene ID:

  3693

• Reactivity:

  Human

• Storage Conditions:

  May be stored at 4 °C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 °C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

• Specificity:

  Recognizes human integrin alphaVbeta5. Does not recognize integrin alphaVbeta3 or alpha5beta1. Binds to the alphaVbeta5 complex. Has a Kd of 2.8 nM in Mn2+, 4.0 nM in Ca2+and 2.9 nM in buffer lacking cation. Thus, cations do not significantly affect the binding to alphaVbeta5. Does not block ligand binding to purified alphaVbeta5, nor does it block cell adhesion mediated through this receptor.

• Other Gene Names:

  [ITGB5; ITGB5]

• Short Name:

  [Integrin alphaV, beta5]

• Other Product Names:

  [integrin beta-5; Integrin beta-5; integrin beta-5; integrin, beta 5]

• NCBI GI Number:

  20127446

• NCBI Accession Number:

  NP_002204.2

• NCBI GB Accession Number:

  NM_002213.3

• Uniprot Accession Number:

  P18084