Products for Research Use Only
RegisterLogin

HS-276

CAT: 0013-GTR19186403-06Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19186403-06Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HS-276 is a potent and selective TAK1 inhibitor with an IC50 of 8.25 nM, also showing activity against CLK2, GCK, ULK2, and MAP4K5. This orally bioavailable compound is a valuable research tool for investigating rheumatoid arthritis mechanisms in both cellular and animal models.
CAS Number
2767422-72-8
Product Name Alternative
TAK1
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.67% (May vary between batches)
Solubility
DMSO:45 mg/mL (107.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.77 mM)
Smiles
C (CC) N1C=2C (N=C1NC (=O) C3=CC (C (N) =O) =CC=C3) =CC=C (CN4CCCCC4) C2
Molecular Formula
C24H29N5O2
Molecular Weight
419.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(6-(Piperidin-1-ylmethyl)-1-propyl-1H-benzo[d]imidazol-2-yl)isophthalamide
CAS Number2767422-72-8
PubChem CID164517032
IUPAC Name3-N-[6-(piperidin-1-ylmethyl)-1-propylbenzimidazol-2-yl]benzene-1,3-dicarboxamide
Molecular FormulaC24H29N5O2
Molecular Weight419.5
XLogP3
Topological Polar Surface Area93.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Heavy Atom Count31
Formal Charge0
Complexity623
SMILES
CCCN1C2=C(C=CC(=C2)CN3CCCCC3)N=C1NC(=O)C4=CC=CC(=C4)C(=O)N
InChI
InChI=1S/C24H29N5O2/c1-2-11-29-21-14-17(16-28-12-4-3-5-13-28)9-10-20(21)26-24(29)27-23(31)19-8-6-7-18(15-19)22(25)30/h6-10,14-15H,2-5,11-13,16H2,1H3,(H2,25,30)(H,26,27,31)
InChIKey
NPEMHKSMWPZEOV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(6-(Piperidin-1-ylmethyl)-1-propyl-1H-benzo[d]imidazol-2-yl)isophthalamide
CAS: 2767422-72-8
CID: 164517032
Formula: C24H29N5O2
MW: 419.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight419.5
XLogP33
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass419.23212518
Monoisotopic Mass419.23212518
Topological Polar Surface Area93.3 Ų
Heavy Atom Count31
Formal Charge0
Complexity623
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19205843-01FTI 276
GTR19205844-01FTI 276 TFA
GTR19036925-01Glycoprotein (276-286)
GTR19276224-01CRBN ligand-276
GTR19264029-01Anticancer agent 276
GTR19209693-01KAA-276 HCl
GTR19257779-01Antibacterial agent 276
GTR19209692-01KAA-276 free base
GTR19223033-01NIR-HS
GTR19218223-01HS-291

Alternative Products

CatalogName
BA3525-25HS-276
A24017-5HS-276 5mg
A24017-10HS-276 10mg
A24017-100HS-276 100mg
A24017-50HS-276 50mg
T11331L-01FTI 276
MBS130120-01KPT-276

Popular Products