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CPL304110

CAT: 0013-GTR19185942-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185942-01Size:25 mg
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Description
CPL304110 is a potent, selective, and orally bioavailable small-molecule inhibitor targeting FGFR1-3. It demonstrates low nanomolar IC50 values against these receptors. This profile makes it a valuable research tool for investigating FGFR-driven pathologies, including certain cancers, in both cellular and animal models.
CAS Number
1627826-19-0
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
COc1cc (CCc2cc (n[nH]2) -c2nc3ccc (cc3[nH]2) N2CCN (C) CC2) cc (OC) c1
Molecular Formula
C25H30N6O2
Molecular Weight
446.54
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

CID 136387462
CAS Number1627826-19-0
PubChem CID136387462
IUPAC Name2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-6-(4-methylpiperazin-1-yl)-1H-benzimidazole
Molecular FormulaC25H30N6O2
Molecular Weight446.5
XLogP3.6
Topological Polar Surface Area82.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count33
Formal Charge0
Complexity606
SMILES
CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=NNC(=C4)CCC5=CC(=CC(=C5)OC)OC
InChI
InChI=1S/C25H30N6O2/c1-30-8-10-31(11-9-30)19-6-7-22-23(15-19)27-25(26-22)24-14-18(28-29-24)5-4-17-12-20(32-2)16-21(13-17)33-3/h6-7,12-16H,4-5,8-11H2,1-3H3,(H,26,27)(H,28,29)
InChIKey
QHCGPJPIPKDWAT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of CID 136387462
CAS: 1627826-19-0
CID: 136387462
Formula: C25H30N6O2
MW: 446.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight446.5
XLogP33.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass446.24302422
Monoisotopic Mass446.24302422
Topological Polar Surface Area82.3 Ų
Heavy Atom Count33
Formal Charge0
Complexity606
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
T62652-01CPL304110

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