Products for Research Use Only

Ruboxistaurin

CAT: 0013-GTR19185553-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185553-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ruboxistaurin (LY333531) is a potent and selective oral inhibitor of PKC beta isoforms, exhibiting competitive, ATP-dependent inhibition with IC50 values of 4.7 nM (PKC beta I) and 5.9 nM (PKC beta II) . It has been widely used in preclinical research, including in vitro signaling studies and in vivo models of diabetic microvascular complications.
CAS Number
169939-94-0
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction
Smiles
CN (C) C[C@@H]1CCn2cc (C3=C (C (=O) NC3=O) c3cn (CCO1) c1ccccc31) c1ccccc21
Molecular Formula
C28H28N4O3
Molecular Weight
468.55
Storage Conditions
-20°C
Notes
For research use only.