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R547

CAT: 0013-GTR19185545-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185545-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
R547 (Ro 4584820) is a highly potent and selective ATP-competitive inhibitor targeting CDK1, CDK2, and CDK4 with Ki values in the low nanomolar range. This investigational compound has been utilized in preclinical research to study cell cycle progression and proliferation in various cancer models, both in vitro and in vivo, during its Phase 1 clinical development.
CAS Number
741713-40-6
Product Name Alternative
R547, R-547, R 547, PKA, Ro 4584820, tumor, Apoptosis, cyclin-dependent, Cyclin dependent kinase, CDK1/CyclinB, CDK2/CyclinE, CDK4/CyclinD1, CDK, inhibit, kinase, multiple, human, Inhibitor, GSK-3, GSK3, Glycogen synthase kinase-3, Glycogen synthase kinase 3
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
90.00% (May vary between batches)
Solubility
DMSO:60 mg/mL (135.92 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COc1ccc (F) c (F) c1C (=O) c1cnc (NC2CCN (CC2) S (C) (=O) =O) nc1N
Molecular Formula
C18H21F2N5O4S
Molecular Weight
441.45
Storage Conditions
-20°C
Notes
For research use only.

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C08782-01R547
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A11190-500R547 500mg
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HY-10014RR547 (Standard)

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