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ALK-IN-22

CAT: 0013-GTR19185533-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185533-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALK-IN-22 is a potent, low-nanomolar inhibitor of ALK and its common resistant mutants (L1196M, G1202R) . It suppresses ALK signaling by reducing phosphorylation of ALK and downstream proteins, leading to apoptosis. This compound is a valuable research tool for investigating ALK-driven tumors in both cellular and animal model systems.
CAS Number
2468219-09-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (N (C) C) (=O) C=1C=2C (=CC (NC=3N=C (NC4=C (C (NC) =O) C=CC=C4) C (Cl) =CN3) =CC2) NC1C
Molecular Formula
C24H24ClN7O2
Molecular Weight
477.95
Storage Conditions
-20°C
Notes
For research use only.

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