Products for Research Use Only

PKRA83

CAT: 0013-GTR19185206-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185206-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PKRA83 is a brain-penetrant, potent small molecule antagonist of prokineticin receptors PKR1 (IC50: 5.0 nM) and PKR2 (IC50: 8.2 nM) . It competitively inhibits PK2 signaling and has demonstrated anti-cancer and anti-angiogenic properties in research models, supporting its use in oncology and neurobiology studies both in vitro and in vivo.
CAS Number
1233926-87-8
Smiles
ClC1=C2C (=CC (CN (C (=O) [C@H]3CN (CC4=CC (OC) =C (F) C=C4) CC3) CC (C) C) =C1) OCCCO2
Molecular Formula
C27H34ClFN2O4
Molecular Weight
505.02
Storage Conditions
-20°C
Notes
For research use only.