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HR-19011

CAT: 0013-GTR19184966-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184966-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HR-19011 (Compound 40) is a small molecule inducer of eIF2α phosphorylation, leading to increased expression of downstream proteins ATF4 and CHOP. It exhibits anti-proliferative activity in the low micromolar range against K562 leukemia cells and PBMCs in vitro, making it a useful research tool for studying the integrated stress response and cellular apoptosis pathways.
CAS Number
2851820-52-3
Product Name Alternative
HR19011, EIF2α activator 1
Field of Research
Cell Biology
Purity
99.89% (May vary between batches)
Solubility
DMSO:20 mg/mL (38.21 mM)
Smiles
N (C1=C (N[C@H]2CC[C@H] (OC3=CC=C (C (F) (F) F) C=C3) CC2) C (=O) C1=O) C4=CC (C (F) (F) F) =CC (C#N) =C4
Molecular Formula
C25H19F6N3O3
Molecular Weight
523.43
Storage Conditions
-20°C
Notes
For research use only.

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