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K20

CAT: 0013-GTR19184794-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184794-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
K20 is a potent and selective KRas G12C inhibitor (IC50: 1.16 nM) demonstrating in vitro anticancer activity in H358 cells (IC50: 0.78 μM) and in vivo tumor growth inhibition (TGI: 41%) . It induces apoptosis by reducing Erk phosphorylation, making it a valuable tool for oncology and signal transduction research.
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C24H20Cl2F4N4O2
Molecular Weight
543.34
Storage Conditions
-20°C
Notes
For research use only.

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