LPLRF-NH2

LPLRF-NH2

• CAS Number: 88280-21-1
• UNSPSC Description: LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons[1][2][3].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/lplrf-nh2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)=O)[C@H](CC(C)C)N
• Molecular Weight: 643.82
• References & Citations: [1]Scheel A, et al. LPLRFamide exerts short-term anorexigenic effects that coincide with magnocellular division of the hypothalamic paraventricular nucleus activation. Gen Comp Endocrinol. 2017 May 15;246:116-119. |[2]Barnard CS, et al. Increases in arterial blood pressure in the rat in response to a new vertebrate neuropeptide, LPLRFamide, and a related molluscan peptide, FMRFamide. Regul Pept. 1984 Apr;8(3):209-15. |[3]Chartrel N, et al. Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides. 2006 May;27(5):1110-20. |[4]Hinuma S, et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol. 2000 Oct;2(10):703-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported