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Windorphen

CAT: 0804-HY-115539-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115539-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Windorphen is a Wnt/β-catenin signal inhibitor that specifically targets the function of the c-terminal transactivation domain of β-catenin-1 but not β-catenin-2. Windorphen selectively targets p300, disrupting the association of the mammalian β-catenin with p300 but not CBP[1].
CAS Number
19881-70-0
Product Name Alternative
CP 526555 (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histone Acetyltransferase; Wnt; β-catenin
Type
Reference compound
Related Pathways
Epigenetics; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/windorphen.html
Purity
99.75
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C/C(C1=CC=C(OC)C=C1)=C(Cl)/C2=CC=C(OC)C=C2
Molecular Formula
C17H15ClO3
Molecular Weight
302.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Jijun Hao, et al. Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen. Cell Rep. 2013 Sep 12;4 (5) :898-904.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS3603107-01Windorphen

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