CD24/Siglec-10 blocking peptide, CSBP

• UNSPSC Description:

  CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Peptides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/cd24-siglec-10-blocking-peptide-csbp.html

• Purity:

  99.59

• Solubility:

  DMSO : 10 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)

• Smiles:

  O=C(O)CC[C@H](C(O)=O)NC([C@@H](CO)NC([C@@H](CC1=CC=C(O)C=C1)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](C(C)C)NC([C@@H](CC(O)=O)NC([C@@H](CC(C)C)N)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  985.09

• References & Citations:

  [1]Wenhui Shen, et al. Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy. J Immunother Cancer. 2023 Jun;11(6):e007068.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported