CD24/Siglec-10 blocking peptide, CSBP

CD24/Siglec-10 blocking peptide, CSBP

• UNSPSC Description: CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell[1].
• Target Antigen: PD-1/PD-L1
• Type: Peptides
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/cd24-siglec-10-blocking-peptide-csbp.html
• Purity: 99.59
• Solubility: DMSO : 10 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
• Smiles: O=C(O)CC[C@H](C(O)=O)NC([C@@H](CO)NC([C@@H](CC1=CC=C(O)C=C1)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](C(C)C)NC([C@@H](CC(O)=O)NC([C@@H](CC(C)C)N)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 985.09
• References & Citations: [1]Wenhui Shen, et al. Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy. J Immunother Cancer. 2023 Jun;11(6):e007068.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported