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Brivanib

CAT: 0013-GTR19188120-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188120-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Brivanib (BMS-540215) is a potent, ATP-competitive VEGFR2 inhibitor (IC50=25 nM) with additional activity against VEGFR-1 and FGFR-1, but significantly less potency against PDGFR-β. This investigational compound has been evaluated in Phase 3 clinical trials for oncology research, supporting its use in both in vitro and in vivo studies of angiogenesis and tumor growth.
CAS Number
649735-46-6
Product Name Alternative
Autophagy, BMS 540215, BMS540215, BMS-540215, Brivanib, Inhibitor, EGFR, FGFR1, Flk1, inhibit, VEGFR2, VEGFR, VEGFR1, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.4 mM) ; H2O:<1 mg/mL; Ethanol:3 mg/mL (8.1 mM) ; DMSO:69 mg/mL (186.3 mM)
Smiles
C[C@@H] (O) COc1cn2ncnc (Oc3ccc4[nH]c (C) cc4c3F) c2c1C
Molecular Formula
C19H19FN4O3
Molecular Weight
370.38
Storage Conditions
-20°C
Notes
For research use only.

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B1325-1Brivanib
B1326-1Brivanib Alaninate
BUP03287-01Brivanib (alaninate)
AR-B02031-01Brivanib-d6
A10254-200Brivanib 200mg
A10254-10Brivanib 10mg

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