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JH295 hydrate

CAT: 0013-GTR19187503Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187503Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JH295 hydrate is a potent, selective, and irreversible Nek2 inhibitor that acts via alkylation of Cys22 (IC50 = 770 nM) . It exhibits high selectivity, showing no activity against Cdk1, Aurora B, or Plk1, and does not disrupt spindle assembly or checkpoint function, making it a valuable chemical probe for studying Nek2's role in cancer and cell cycle research.
Field of Research
Signal Transduction
Molecular Formula
C18H18N4O3
Molecular Weight
338.36
Storage Conditions
-20°C
Notes
For research use only.

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