Products for Research Use Only

XMD8-92

CAT: 0013-GTR19177988-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177988-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XMD8-92 is a potent and selective small-molecule inhibitor of BMK1/ERK5, exhibiting a high-affinity binding dissociation constant (Kd) of 80 nM. This compound is a valuable research tool for investigating the ERK5 signaling pathway in both cellular and animal models, particularly in studies related to cancer, cardiovascular biology, and inflammation.
CAS Number
1234480-50-2
Product Name Alternative
Cancer, bFGF, BMI-1, BMI1, inhibit, Extracellular signal regulated kinases, ERK, Epigenetic Reader Domain, EpigeneticReaderDomain, HMEC, leukemia, Inhibitor, protein, promyelocytic, XMD892, XMD-8-92, XMD8-92, XMD8 92
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction
Purity
98.19% (May vary between batches)
Solubility
DMSO:19 mg/mL (40.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.21 mM)
Smiles
CCOc1cc (ccc1Nc1ncc2N (C) C (=O) c3ccccc3N (C) c2n1) N1CCC (O) CC1
Molecular Formula
C26H30N6O3
Molecular Weight
474.55
Storage Conditions
-20°C
Notes
For research use only.