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VU0463271

CAT: 0013-GTR19177860-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177860-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0463271 is a potent and selective KCC2 antagonist (IC50 = 61 nM) with >100-fold selectivity over NKCC1 and minimal off-target activity. It is a valuable research tool for investigating KCC2 function in neuronal excitability, synaptic inhibition, and related pathophysiology in both in vitro and in vivo models.
CAS Number
1391737-01-1
Product Name Alternative
Inhibit, KcsA, KCC2, Inhibitor, N-Cyclopropyl-N- (4-methyl-2-thiazolyl) -2-[ (6-phenyl-3-pyridazinyl) thio]acetamide, VU0463271, VU-0463271, VU 0463271, PotassiumChannel, Potassium Channel
Field of Research
Pharmacology & Drug Discovery
Purity
97.84% (May vary between batches)
Solubility
DMSO:3.83 mg/mL (10.01 mM)
Smiles
Cc1csc (n1) N (C1CC1) C (=O) CSc1ccc (nn1) -c1ccccc1
Molecular Formula
C19H18N4OS2
Molecular Weight
382.5
Storage Conditions
-20°C
Notes
For research use only.

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