SIM-688

CAT: 0013-GTR19177855-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19177855-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

SIM-688 is a selective, orally bioavailable small molecule that inhibits estrogen receptor-mediated NF-κB transcriptional activity, demonstrating an IC50 of 122 nM in HAECT-1 cells. This inhibitor is a valuable research tool for studying inflammatory and oncogenic signaling pathways in both cellular and animal models.

CAS Number

796854-35-8

Product Name Alternative

Progestogen Receptor, progestogenReceptor, SIM 688, SIM688, NF-κB-luc, NF-κB, NFkB, NF-kB, NFκB, Erα, Estrogen Receptor, EstrogenReceptor

Field of Research

Metabolism Research, Signal Transduction

Purity

99.12% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (5.93 mM) ; DMSO:90 mg/mL (161.69 mM)

Smiles

COc1ccccc1[C@H] (c1cccc2ccccc12) [C@@] (C) (C#N) C (=O) N1CCC (CC1) c1cccc (c1) C (F) (F) F

Molecular Formula

C34H31F3N2O2

Molecular Weight

556.62

Storage Conditions

-20°C

Notes

For research use only.

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