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Benoxaprofen

CAT: 0804-HY-13568-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13568-01Size:1 mg
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Description
Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen is a relatively weak inhibitor of cyclooxygenase in in vitro systems, inhibits lipoxygenase in other systems, and inhibits monocyte migration in some animal models of inflammation[1][2].
CAS Number
51234-28-7
Product Name Alternative
LRCL 3794
UNSPSC
12352005
Hazard Statement
H301, H413
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/benoxaprofen.html
Purity
99.24
Solubility
10 mM in DMSO
Smiles
O=C(O)C(C)C1=CC=C(OC(C2=CC=C(Cl)C=C2)=N3)C3=C1
Molecular Formula
C16H12ClNO3
Molecular Weight
301.72
Precautions
H301, H413
References & Citations
[1]Cashin CH, et al. The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis. J Pharm Pharmacol. 1977;29 (6) :330-336.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported