Benoxaprofen

• Description :

  Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen is a relatively weak inhibitor of cyclooxygenase in in vitro systems, inhibits lipoxygenase in other systems, and inhibits monocyte migration in some animal models of inflammation[1][2].

• Product Name Alternative :

  LRCL 3794

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H413

• Target :

  COX

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/benoxaprofen.html

• Purity :

  99.24

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C(C)C1=CC=C(OC(C2=CC=C(Cl)C=C2)=N3)C3=C1

• Molecular Formula :

  C16H12ClNO3

• Molecular Weight :

  301.72

• Precautions :

  H301, H413

• References & Citations :

  [1]Cashin CH, et al. The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis. J Pharm Pharmacol. 1977;29 (6) :330-336.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [51234-28-7]