Products for Research Use Only
RegisterLogin

Fludarabine

CAT: 0013-GTR19177581-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19177581-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fludarabine is a fluorinated purine analog that inhibits nucleic acid synthesis and STAT1 activation. It is widely used in leukemia and lymphoma research, with applications in both in vitro cell culture studies and in vivo animal models to investigate its antitumor mechanisms.
CAS Number
21679-14-1
Product Name Alternative
F-ara-A; NSC118218
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
DNA synthesis inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml)
Smiles
NC1=C2N=CN ([C@@H]3O[C@H] (CO) [C@@H] (O) [C@@H]3O) C2=NC (F) =N1
Molecular Formula
C10H12FN5O4
Molecular Weight
285.2
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine

Chemical Information

Fludarabine

(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9-purinyl)-5-(hydroxymethyl)oxolane-3,4-diol is a purine nucleoside.

CAS Number21679-14-1
PubChem CID657237
IUPAC Name(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular FormulaC10H12FN5O4
Molecular Weight285.23
XLogP-0.6
Topological Polar Surface Area140
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity367
SMILES
C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)F)N
InChI
InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
InChIKey
HBUBKKRHXORPQB-FJFJXFQQSA-N
Chemical Structure
2D Structure
2D structure of Fludarabine
CAS: 21679-14-1
CID: 657237
Formula: C10H12FN5O4
MW: 285.23
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight285.23
XLogP3-0.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count2
Exact Mass285.08733204
Monoisotopic Mass285.08733204
Topological Polar Surface Area140 Ų
Heavy Atom Count20
Formal Charge0
Complexity367
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T1038-01Fludarabine

Popular Products