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BRM014

CAT: 0013-GTR19178057-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178057-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRM/BRG1 ATP Inhibitor-1 is a potent, allosteric dual inhibitor of the SWI/SNF chromatin remodeling ATPases SMARCA2 (BRM) and SMARCA4 (BRG1), with IC50 values below 5 nM. This small molecule is a valuable chemical probe for studying SWI/SNF function in oncology and epigenetics research, both in vitro and in vivo.
CAS Number
2270879-17-7
Product Name Alternative
EpigeneticReaderDomain, Epigenetic Reader Domain, Inhibitor, inhibit, anticancer, ATPase inhibitor, (BRG1) /SMARCA4, (BRM) /SMARCA2, BRM, BRG1, BRM/BRG1, BRM/BRG1 ATP Inhibitor 1, BRM/BRG1 ATP Inhibitor1, BRM/BRG-1 ATP Inhibitor-1, BRM/BRG1 ATP Inhibitor-1, dual inhibitor
Field of Research
Epigenetics & Chromatin
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (70 mg/ml)
Smiles
OCc1cnc (F) cc1NC (=O) Nc1cc (ns1) C (F) F
Molecular Formula
C11H9F3N4O2S
Molecular Weight
318.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[3- (Difluoromethyl) isothiazol-5-yl]-3-[2-fluoro-5- (hydroxymethyl) pyridin-4-yl]urea

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Alternative Products

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abx283473-01BRM014
TBI5244-1MGBRM014, BRM / BRG1 ATPase inhibitor
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