Products for Research Use Only
RegisterLogin

ITI-214

CAT: 0013-GTR19177210-07Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19177210-07Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ITI-214 is a highly potent and selective picomolar inhibitor of PDE1 (Ki = 58 pM), demonstrating minimal off-target activity. This tool compound is valuable for investigating PDE1's role in neurological and cardiovascular research, with utility in both cellular assays and animal models.
CAS Number
1642303-38-5
Product Name Alternative
Cognitive, CNS-active, PDE, PDE1, oral, inhibit, ITI214, ITI-214, ITI 214, motor, Inhibitor, selective, phosphodiesterase, Phosphodiesterase (PDE)
Field of Research
Metabolism Research
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.3 mM) ; DMSO:30 mg/mL (49.54 mM)
Smiles
O=C (C1=C (NC2=CC=CC=C2) N (CC3=CC=C (C4=NC (F) =CC=C4) C=C3) N=C1N56) N (C) C5=N[C@@]7 ([H]) [C@]6 ([H]) CCC7.O=P (O) (O) O
Molecular Formula
C29H29FN7O5P
Molecular Weight
605.56
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Lenrispodun Phosphate

See also: Lenrispodun (has active moiety).

CAS Number1642303-38-5
PubChem CID72704434
IUPAC Name(11R,15S)-5-anilino-4-[[4-(6-fluoro-2-pyridinyl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoric acid
Molecular FormulaC29H29FN7O5P
Molecular Weight605.6
Topological Polar Surface Area156
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Heavy Atom Count43
Formal Charge0
Complexity953
SMILES
CN1C(=O)C2=C(N(N=C2N3C1=N[C@H]4[C@@H]3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7.OP(=O)(O)O
InChI
InChI=1S/C29H26FN7O.H3O4P/c1-35-28(38)25-26(31-20-7-3-2-4-8-20)36(34-27(25)37-23-11-5-10-22(23)33-29(35)37)17-18-13-15-19(16-14-18)21-9-6-12-24(30)32-21;1-5(2,3)4/h2-4,6-9,12-16,22-23,31H,5,10-11,17H2,1H3;(H3,1,2,3,4)/t22-,23+;/m1./s1
InChIKey
ZPIAAFIYOPWWJL-RFPXDPOKSA-N
Chemical Structure
2D Structure
2D structure of Lenrispodun Phosphate
CAS: 1642303-38-5
CID: 72704434
Formula: C29H29FN7O5P
MW: 605.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight605.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass605.19518221
Monoisotopic Mass605.19518221
Topological Polar Surface Area156 Ų
Heavy Atom Count43
Formal Charge0
Complexity953
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19236277-01ITI-333
GTR19174875-01HMN-214
GTR19238982-01AJI-214
GTR19232128-01VVD-214
GTR19263761-01Indolimine-214
GTR18077769ITI-H3 antibody
GTR18904156-01Tyrosinase (206-214)
GTR19276125-01CRBN ligand-214
GTR19233950-01Anticancer agent 214
GTR19034883-01IGRP (206-214)

Alternative Products

CatalogName
E7587ITI-214
522622ITI-214 phosphate
HY-12501-01ITI-214 (free base)
T11688-01ITI-214 free base
T88764-01ITI-333
A5413-50HMN-214
BA3955-5.1VVD-214
HY-172537Indolimine-214
RR214-RK4F.IRoboRocker 214

Popular Products