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Lanraplenib

CAT: 0013-GTR19177166-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177166-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lanraplenib (GS-9876) is a potent and selective oral inhibitor of spleen tyrosine kinase (SYK) with an IC50 of 9.5 nM. It is being developed for inflammatory diseases and has been shown to inhibit SYK in platelet GPVI signaling without affecting bleeding time in preclinical and clinical studies.
CAS Number
1800046-95-0
Product Name Alternative
Syk, SYK, Spleen tyrosine kinase, inhibit, Lanraplenib, Inhibitor, GS9876, GS-9876, GS 9876
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.35% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (93.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM)
Smiles
Nc1cncc (n1) -c1cn2ccnc2c (Nc2ccc (cc2) N2CCN (CC2) C2COC2) n1
Molecular Formula
C23H25N9O
Molecular Weight
443.5
Storage Conditions
-20°C
Notes
For research use only.

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