Products for Research Use Only
RegisterLogin

LDH-IN-1

CAT: 0013-GTR19177163-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19177163-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LDH-IN-1 is a potent, pyrazole-derived inhibitor of human lactate dehydrogenase isoforms LDHA and LDHB, exhibiting IC50 values of 32 nM and 27 nM, respectively. This compound is a valuable research tool for investigating cancer metabolism, particularly in in vitro studies targeting glycolysis-dependent tumor cell proliferation.
CAS Number
1964515-43-2
Product Name Alternative
Inhibit, Inhibitor, Lactate Dehydrogenase, LDH IN 1, LDH, LDHA, LDHB, LDHIN1, LDH-IN-1
Field of Research
Metabolism Research
Purity
99.60% (May vary between batches)
Solubility
DMSO:50 mg/mL (87.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.5 mM)
Smiles
NS (=O) (=O) c1ccc (Cc2c (CC3CC3) n (nc2-c2cccc (c2) -c2ccccc2) -c2nc (cs2) C (O) =O) cc1
Molecular Formula
C30H26N4O4S2
Molecular Weight
570.68
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Ldh-IN-1
CAS Number1964515-43-2
PubChem CID131955127
IUPAC Name2-[5-(cyclopropylmethyl)-3-(3-phenylphenyl)-4-[(4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
Molecular FormulaC30H26N4O4S2
Molecular Weight570.7
XLogP6.3
Topological Polar Surface Area165
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Heavy Atom Count40
Formal Charge0
Complexity975
SMILES
C1CC1CC2=C(C(=NN2C3=NC(=CS3)C(=O)O)C4=CC=CC(=C4)C5=CC=CC=C5)CC6=CC=C(C=C6)S(=O)(=O)N
InChI
InChI=1S/C30H26N4O4S2/c31-40(37,38)24-13-11-19(12-14-24)15-25-27(16-20-9-10-20)34(30-32-26(18-39-30)29(35)36)33-28(25)23-8-4-7-22(17-23)21-5-2-1-3-6-21/h1-8,11-14,17-18,20H,9-10,15-16H2,(H,35,36)(H2,31,37,38)
InChIKey
ALJORCZKMBZYCR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ldh-IN-1
CAS: 1964515-43-2
CID: 131955127
Formula: C30H26N4O4S2
MW: 570.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight570.7
XLogP36.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass570.13954767
Monoisotopic Mass570.13954767
Topological Polar Surface Area165 Ų
Heavy Atom Count40
Formal Charge0
Complexity975
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR17964295Ldh-1 Antibody
GTR19240935-01LDH-IN-3
GTR17983901Ldh Antibody
GTR18074462-01LDH-A Antibody
GTR17983903Ldh Antibody
GTR17983183Ldh Antibody
GTR17969642Ldh Antibody
GTR18273229LDH-A Conjugated Antibody
GTR18084280Anti-LDH-B
GTR18910577LDH-A Recombinant Protein

Alternative Products

CatalogName
MBS3612273-01LDH-IN-1
A19496-50LDH-IN-1 50mg
A19496-5LDH-IN-1 5mg
A19496-25LDH-IN-1 25mg
A19496-1LDH-IN-1 1mg
A19496-100LDH-IN-1 100mg
A19496-10LDH-IN-1 10mg
A19496-2LDH-IN-1 2mg
227048Lactate Dehydrogenase (LDH, LDH-M, LDH-A)
227048-PELactate Dehydrogenase (LDH, LDH-M, LDH-A) (PE)

Popular Products