FIDAS-3

CAT: 0013-GTR19176706-07Size: 200 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19176706-07Size:200 mg

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Description

FIDAS-3 is a stilbene-based small molecule that potently inhibits MAT2A (IC50 = 4.9 μM) by competing with its cofactor SAM. This Wnt pathway inhibitor demonstrates anticancer activity and is a useful chemical probe for studying methionine metabolism and epigenetics in cancer cell lines and in vivo models.

CAS Number

1266684-01-8

Product Name Alternative

Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, SAH, S-adenosylmethionine, SAM, βcatenin, β-catenin, CyclinD1, c-Myc, beta-catenin, betacatenin, bcatenin, anti-cancer, anti-proliferation, Methionine Adenosyltransferase, Methionine Adenosyltransferase (MAT), Methionine S-adenosyltransferase 2A (MAT2A), MethionineAdenosyltransferase (MAT), MethionineAdenosyltransferase, inhibit, Inhibitor, FIDAS 3, FIDAS3, FIDAS-3, MAT, MAT2A, MATA2

Field of Research

Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.75% (May vary between batches)

Solubility

DMSO:90 mg/mL (347.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.73 mM)

Smiles

CN (C) c1ccc (\C=C\c2c (F) cccc2F) cc1

Molecular Formula

C16H15F2N

Molecular Weight

259.29

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Fidas-3

CAS Number	1266684-01-8
PubChem CID	51039205
IUPAC Name	4-[(E)-2-(2,6-difluorophenyl)ethenyl]-N,N-dimethylaniline
Molecular Formula	C16H15F2N
Molecular Weight	259.29
XLogP	4.5
Topological Polar Surface Area	3.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Heavy Atom Count	19
Formal Charge	0
Complexity	285

SMILES

CN(C)C1=CC=C(C=C1)/C=C/C2=C(C=CC=C2F)F

InChI

InChI=1S/C16H15F2N/c1-19(2)13-9-6-12(7-10-13)8-11-14-15(17)4-3-5-16(14)18/h3-11H,1-2H3/b11-8+

InChIKey

YBJDCOLXJYDHOM-DHZHZOJOSA-N

Chemical Structure

2D Structure

CAS: 1266684-01-8

CID: 51039205

Formula: C16H15F2N

MW: 259.29

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	259.29
XLogP3	4.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	259.11725581
Monoisotopic Mass	259.11725581
Topological Polar Surface Area	3.2 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	285
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Catalog	Name
RAC68401-01	FIDAS-3
BA4942-50	FIDAS-5

FIDAS-3

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