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NEO 376

CAT: 0013-GTR19176568-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176568-05Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NEO 376 (SPI-376) is a small molecule research compound that acts as a multi-receptor modulator, targeting serotonin 5-HT1, GABA, and dopamine receptors. Its demonstrated antipsychotic activity makes it a candidate for in vitro and in vivo neuropharmacology studies, particularly in psychiatric disorder research.
CAS Number
496921-73-4
Product Name Alternative
Dopamine Receptor, DopamineReceptor, 5-HT1, 5-HT1 Receptor, 5-HT Receptor, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, Inhibitor, Gamma-aminobutyric acid Receptor, GABAReceptor, GABA Receptor, GABA, inhibit, NEO 376, NEO376, NEO-376, SPI 376, SPI376, SPI-376, Serotonin Receptor, γ-Aminobutyric acid Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.59 mM) ; DMSO:45 mg/mL (125.74 mM)
Smiles
Clc1cccc (c1) N1CCN (CCn2ccc3c2CCCC3=O) CC1
Molecular Formula
C20H24ClN3O
Molecular Weight
357.88
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-6,7-dihydro-5H-indol-4-one
CAS Number496921-73-4
PubChem CID9906770
IUPAC Name1-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-6,7-dihydro-5H-indol-4-one
Molecular FormulaC20H24ClN3O
Molecular Weight357.9
XLogP3
Topological Polar Surface Area28.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity466
SMILES
C1CC2=C(C=CN2CCN3CCN(CC3)C4=CC(=CC=C4)Cl)C(=O)C1
InChI
InChI=1S/C20H24ClN3O/c21-16-3-1-4-17(15-16)23-12-9-22(10-13-23)11-14-24-8-7-18-19(24)5-2-6-20(18)25/h1,3-4,7-8,15H,2,5-6,9-14H2
InChIKey
CQSQHUPRBBCQRE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-6,7-dihydro-5H-indol-4-one
CAS: 496921-73-4
CID: 9906770
Formula: C20H24ClN3O
MW: 357.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight357.9
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass357.1607901
Monoisotopic Mass357.1607901
Topological Polar Surface Area28.5 Ų
Heavy Atom Count25
Formal Charge0
Complexity466
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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