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Prilocaine hydrochloride

CAT: 0013-GTR19175982-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175982-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prilocaine HCl is an amino amide local anesthetic that inhibits neuronal voltage-gated sodium channels, blocking sodium ion influx and action potential propagation. It is widely used in in vitro electrophysiology studies and in vivo models for regional anesthesia research.
CAS Number
1786-81-8
Product Name Alternative
Inhibit, K (+), local, Na+/K+ ATPase, Na (+), neurotoxic, Inhibitor, anaesthetize, Prilocaine, Prilocaine HCl, Prilocaine hydrochloride, Prilocaine Hydrochloride, Xylonest, SodiumChannel, Sodium potassium pump, Sodium Channel, Propitocaine hydrochloride, Propitocaine Hydrochloride
Field of Research
Pharmacology & Drug Discovery
Purity
99.97% (May vary between batches)
Solubility
DMSO:60 mg/mL (233.67 mM)
Smiles
Cl.CCCNC (C) C (=O) Nc1ccccc1C
Molecular Formula
C13H21ClN2O
Molecular Weight
256.77
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Prilocaine Hydrochloride

Prilocaine Hydrochloride is the hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation.

CAS Number1786-81-8
PubChem CID92163
IUPAC NameN-(2-methylphenyl)-2-(propylamino)propanamide;hydrochloride
Molecular FormulaC13H21ClN2O
Molecular Weight256.77
Topological Polar Surface Area41.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Heavy Atom Count17
Formal Charge0
Complexity218
SMILES
CCCNC(C)C(=O)NC1=CC=CC=C1C.Cl
InChI
InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
InChIKey
BJPJNTKRKALCPP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Prilocaine Hydrochloride
CAS: 1786-81-8
CID: 92163
Formula: C13H21ClN2O
MW: 256.77
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight256.77
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass256.1342410
Monoisotopic Mass256.1342410
Topological Polar Surface Area41.1 Ų
Heavy Atom Count17
Formal Charge0
Complexity218
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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