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PTC299

CAT: 0013-GTR19175915-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175915-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTC299 is an orally bioavailable small molecule that selectively inhibits VEGFA protein synthesis post-transcriptionally and potently targets dihydroorotate dehydrogenase (DHODH) . It has been investigated in preclinical in vitro and in vivo studies for its potential application in angiogenesis-dependent research areas, including oncology.
CAS Number
1256565-36-2
Product Name Alternative
Dihydroorotate Dehydrogenase, DHODH, DNA/RNA Synthesis, cancer, (4-chlorophenyl) (1S) -6-chloro-1- (4-methoxyphenyl) -1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate, oral, off-target, kinase, inhibit, myelosuppression, malignancies, hematologic, Inhibitor, Emvododstat, PTC299, PTC-299, PTC 299, Vascular endothelial growth factor receptor, VEGFR
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction
Purity
99.19% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.14 mM) ; DMSO:50 mg/mL (106.99 mM)
Smiles
COc1ccc (cc1) [C@@H]1N (CCc2c1[nH]c1ccc (Cl) cc21) C (=O) Oc1ccc (Cl) cc1
Molecular Formula
C25H20Cl2N2O3
Molecular Weight
467.34
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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BA3974-1PTC299
A18935-25PTC299 25mg
A18935-10PTC299 10mg
A18935-5PTC299 5mg
A18935-50PTC299 50mg
A18935-1PTC299 1mg
C01464-5mgEmvododstat (PTC299)
A18935-100PTC299 100mg
A18935-10mM-DPTC299 10mM * 1mL in DMSO

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