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SBI-477

CAT: 0013-GTR19175819-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175819-01Size:1 mg
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Description
SBI-477 is a chemical probe that stimulates insulin signaling by inhibiting the transcription factor MondoA. This action coordinately reduces triglyceride synthesis and increases basal glucose uptake in human skeletal myocytes, making it a useful tool for studying metabolism and insulin resistance in vitro.
CAS Number
781628-99-7
Product Name Alternative
MondoA, inhibit, Inhibitor, SBI 477, SBI477, SBI-477
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.08% (May vary between batches)
Solubility
DMSO:45 mg/mL (93.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.14 mM)
Smiles
COc1ccc (cc1) -c1csc (NC (=O) c2ccc (OCC (=O) N3CCOCC3) c (OC) c2) n1
Molecular Formula
C24H25N3O6S
Molecular Weight
483.54
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide
CAS Number781628-99-7
PubChem CID2469116
IUPAC Name3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide
Molecular FormulaC24H25N3O6S
Molecular Weight483.5
XLogP2.9
Topological Polar Surface Area127
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count34
Formal Charge0
Complexity671
SMILES
COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC(=C(C=C3)OCC(=O)N4CCOCC4)OC
InChI
InChI=1S/C24H25N3O6S/c1-30-18-6-3-16(4-7-18)19-15-34-24(25-19)26-23(29)17-5-8-20(21(13-17)31-2)33-14-22(28)27-9-11-32-12-10-27/h3-8,13,15H,9-12,14H2,1-2H3,(H,25,26,29)
InChIKey
SJPVXFZDWAIFFT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide
CAS: 781628-99-7
CID: 2469116
Formula: C24H25N3O6S
MW: 483.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight483.5
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass483.14640670
Monoisotopic Mass483.14640670
Topological Polar Surface Area127 Ų
Heavy Atom Count34
Formal Charge0
Complexity671
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BUP08927-01SBI-477
HY-124417-01SBI-477 analog
A18962-50SBI-477 50mg
A18962-500SBI-477 500mg
A18962-1SBI-477 1mg
A18962-25SBI-477 25mg
A18962-5SBI-477 5mg
A18962-100SBI-477 100mg
A18962-10SBI-477 10mg
A18962-10mM-DSBI-477 10mM * 1mL in DMSO

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