Products for Research Use Only
RegisterLogin

Tyrphostin AG1433

CAT: 0013-GTR19175671-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19175671-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tyrphostin AG1433 is a dual inhibitor of the PDGFRβ and VEGFR-2 (KDR) tyrosine kinases with IC50 values of 5.0 μM and 9.3 μM, respectively. This compound is used in biochemical and cellular research to study angiogenesis and tumor growth pathways in both in vitro and in vivo experimental models.
CAS Number
168835-90-3
Product Name Alternative
Cytotoxicity, AG 1433, AG1433, AG-1433, angiogenesis, tyrosine, ATM, Flk1, Flk-1, Inhibitor, inhibit, KDR, kinases, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, SU 1433, SU1433, SU-1433, Vascular endothelial growth factor receptor, VEGFR, VEGFR2, VEGFR-2, Tyrphostin AG 1433, Tyrphostin AG1433, Tyrphostin AG-1433
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.51% (May vary between batches)
Solubility
DMSO:3.06 mg/mL (11.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.76 mM)
Smiles
Cc1cc2ncc (nc2cc1C) -c1ccc (O) c (O) c1
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol

Tyrphostin AG 1433 is a member of the Tyrphostin family of tyrosine kinase inhibitors that selectively inhibits platelet-derived growth factor beta-receptor kinase and angiogenesis. (NCI)

CAS Number168835-90-3
PubChem CID2050
IUPAC Name4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol
Molecular FormulaC16H14N2O2
Molecular Weight266.29
XLogP2.9
Topological Polar Surface Area66.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count20
Formal Charge0
Complexity338
SMILES
CC1=CC2=NC=C(N=C2C=C1C)C3=CC(=C(C=C3)O)O
InChI
InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3
InChIKey
SMKFYHOKXJUJOT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol
CAS: 168835-90-3
CID: 2050
Formula: C16H14N2O2
MW: 266.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight266.29
XLogP32.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass266.105527694
Monoisotopic Mass266.105527694
Topological Polar Surface Area66.2 Ų
Heavy Atom Count20
Formal Charge0
Complexity338
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19200564-01AG1433
GTR19167547-01Tyrphostin AG30
GTR19201668-01Tyrphostin A25
GTR19200501-01Tyrphostin 47
GTR19166415-01Tyrphostin A1
GTR19160080-01Tyrphostin 9
GTR19250500-01Tyrphostin 63
GTR19173850-01Tyrphostin 9
GTR19172461-01Tyrphostin 23
GTR19211123-01Tyrphostin AG17

Alternative Products

CatalogName
T13238-01Tyrphostin AG1433
HY-119757ATyrphostin AG1433 (hydrochloride)
A24171-10Tyrphostin AG1433 (SU1433) 10mg
A24171-5Tyrphostin AG1433 (SU1433) 5mg
A24171-50Tyrphostin AG1433 (SU1433) 50mg
A24171-100Tyrphostin AG1433 (SU1433) 100mg
T23660-01AG1433
B1494-50Tyrphostin 9
A4681-50Tyrphostin A1
HY-118532-01Tyrphostin AG30

Popular Products