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CDDO-dhTFEA

CAT: 0013-GTR19176379-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176379-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDDO-dhTFEA is a synthetic oleanane triterpenoid that dually activates the Nrf2 antioxidant pathway and inhibits the NF-κB inflammatory pathway. It has demonstrated efficacy in preclinical CKD models, reducing fibrosis, inflammation, and improving hemodynamics, supporting its research use in oxidative stress and fibrotic diseases.
CAS Number
1191265-33-4
Product Name Alternative
Inhibitor, Nrf2, Keap1-Nrf2, inhibit, NF-κB, NF-kB, NFkB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB, CDDOdhTFEA, CDDO-dhTFEA, CDDO dhTFEA, RTA dh 404, RTA dh404, RTA dh-404
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
95.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.74 mM) ; DMSO:100 mg/mL (174 mM)
Smiles
[H][C@@]12CC (C) (C) CC[C@@]1 (CC[C@]1 (C) [C@]2 ([H]) C (=O) C[C@@]2 ([H]) [C@@]1 (C) CC[C@@]1 ([H]) C (C) (C) C (=O) C (=C[C@]21C) C#N) C (=O) NCC (F) (F) F
Molecular Formula
C33H45F3N2O3
Molecular Weight
574.72
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
MBS3844204-01CDDO-dhTFEA
A19751-100CDDO-dhTFEA 100mg
A19751-500CDDO-dhTFEA 500mg
A19751-10CDDO-dhTFEA 10mg
A19751-2CDDO-dhTFEA 2mg
A19751-1CDDO-dhTFEA 1mg
A19751-50CDDO-dhTFEA 50mg
A19751-25CDDO-dhTFEA 25mg
A19751-5CDDO-dhTFEA 5mg
A19751-10mM-DCDDO-dhTFEA 10mM * 1mL in DMSO

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