Shield-1

CAT: 0013-GTR19175546-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19175546-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Shield-1 is a cell-permeable, high-affinity ligand for FKBP12 that stabilizes mutant FKBP fusion proteins, enabling their conditional expression. This small molecule is utilized in both in vitro and in vivo studies for controlling protein stability within chemical biology and targeted protein degradation research.

CAS Number

914805-33-7

Product Name Alternative

Destabilization domain, inhibit, NIH3T3, HEK293, Inhibitor, high-affinity ligand, FK506-binding protein, FKBP, Shld 1, Shld1, Shld-1, Shield 1, Shield1, Shield-1

Field of Research

Cell Biology, Immunology & Inflammation

Purity

98.05% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.68 mM) ; DMSO:250 mg/mL (333.82 mM)

Smiles

CC[C@H] (C (=O) N1CCCC[C@H]1C (=O) O[C@H] (CCc1ccc (OC) c (OC) c1) c1cccc (OCCN2CCOCC2) c1) c1cc (OC) c (OC) c (OC) c1

Molecular Formula

C42H56N2O10

Molecular Weight

748.9

Storage Conditions

-20°C

Notes

For research use only.

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Alternative Products

Catalog	Name
466066-01	Shield 1
T13884-01	Shield-1
A19833-50	Shield-1 50mg
A19833-25	Shield-1 25mg
A19833-10	Shield-1 10mg
A19833-5	Shield-1 5mg
A19833-500	Shield-1 500mg
A19833-100	Shield-1 100mg
A19833-1	Shield-1 1mg

Shield-1

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