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A-385358

CAT: 0013-GTR19175497-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175497-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-385358 is a potent and selective small molecule inhibitor of Bcl-xL, exhibiting a Ki of 0.80 nM, with 84-fold selectivity over Bcl-2. This compound is a valuable research tool for studying apoptosis mechanisms and has been utilized in both in vitro and in vivo models to investigate cancer biology and therapeutic resistance.
CAS Number
406228-55-5
Product Name Alternative
Inhibit, Inhibitor, Bcl-2 Family, Bcl-2, Bcl-xL, A385358, A-385358, A 385358
Field of Research
Cell Biology
Purity
97.40% (May vary between batches)
Solubility
DMSO:45 mg/mL (70.33 mM) ;10% DMSO+90% Saline:2 mg/mL (3.13 mM)
Smiles
CN (C) CC[C@H] (CSc1ccccc1) Nc1ccc (cc1[N+] ([O-]) =O) S (=O) (=O) NC (=O) c1ccc (cc1) N1CCC (C) (C) CC1
Molecular Formula
C32H41N5O5S2
Molecular Weight
639.83
Storage Conditions
-20°C
Notes
For research use only.

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