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A-443654

CAT: 0013-GTR19175496-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175496-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-443654 is a potent pan-Akt inhibitor with equipotent activity against Akt1, Akt2, and Akt3 isoforms, exhibiting a cellular Ki of 160 pM. This compound is widely used in biochemical and cellular research to investigate the PI3K/Akt signaling pathway in cancer and metabolic studies, with applications in both in vitro and in vivo experimental models.
CAS Number
552325-16-3
Product Name Alternative
PKB, PKA, PKCγ, PKCδ, SRC, S6 Kinase, S6Kinase, Protein kinase B, RSK2, inhibit, KDR, ERK2, GSK3, GSK-3β, GSK3β, Flt1, Inhibitor, MAPK, MAPK-AP2, CDK2, Casein Kinase, CaseinKinase, Chk1, CK2, cKIT, Akt, A 443654, A443654, A-443654, Akt1, Akt3, Akt2
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.73% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.06 mM) ; DMSO:100 mg/mL (251.59 mM)
Smiles
C ([C@@H] (COC=1C=C (C=NC1) C=2C=C3C (=CC2) NN=C3C) N) C=4C=5C (NC4) =CC=CC5
Molecular Formula
C24H23N5O
Molecular Weight
397.47
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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E1125-100mgA-443654
A11287-50A-443654 50mg
A11287-25A-443654 25mg
A11287-10A-443654 10mg
A11287-1A-443654 1mg
A11287-500A-443654 500mg
A11287-100A-443654 100mg
A11287-2A-443654 2mg

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