Products for Research Use Only

Etripamil

CAT: 0013-GTR19175310-02Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175310-02Size:2 mg
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Description
Etripamil
CAS Number
1593673-23-4
Product Name Alternative
Ca channels, Calcium Channel, Ca2+ channels, CalciumChannel, (-) -MSP-2017, inhibit, MSP-2017, MSP2017, MSP 2017, L-type calcium channel, Inhibitor, Etripamil
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.95% (May vary between batches)
Solubility
Ethanol:110 mg/mL (243.05 mM)
Smiles
COC (=O) c1cccc (CCN (C) CCC[C@] (C#N) (C (C) C) c2ccc (OC) c (OC) c2) c1
Molecular Formula
C27H36N2O4
Molecular Weight
452.59
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Etripamil

Etripamil is a nondihydropyridine, L-type calcium channel blocker. It is a fast-acting drug with a short duration of action. The nasal formulation of etripamil was first approved by the FDA on December 12, 2025 for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults.

CAS Number1593673-23-4
PubChem CID91824132
IUPAC Namemethyl 3-[2-[[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]-methylamino]ethyl]benzoate
Molecular FormulaC27H36N2O4
Molecular Weight452.6
XLogP3.7
Topological Polar Surface Area71.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count13
Heavy Atom Count33
Formal Charge0
Complexity645
SMILES
CC(C)[C@](CCCN(C)CCC1=CC(=CC=C1)C(=O)OC)(C#N)C2=CC(=C(C=C2)OC)OC
InChI
InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1
InChIKey
VAZNEHLGJGSQEL-MHZLTWQESA-N
Chemical Structure
2D Structure
2D structure of Etripamil
CAS: 1593673-23-4
CID: 91824132
Formula: C27H36N2O4
MW: 452.6
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight452.6
XLogP33.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count13
Exact Mass452.26750763
Monoisotopic Mass452.26750763
Topological Polar Surface Area71.8 Ų
Heavy Atom Count33
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes