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GN44028

CAT: 0013-GTR19175258-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175258-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GN44028 is a potent small molecule inhibitor of hypoxia-inducible factor 1 (HIF-1) with an IC50 of 14 nM. It specifically blocks hypoxia-induced HIF-1α transcriptional activity without affecting its mRNA, protein levels, or heterodimerization. This compound is a valuable research tool for studying hypoxia signaling in cancer and other diseases in cellular models.
CAS Number
1421448-26-1
Product Name Alternative
Cancer, colorectal cancer, PN12, N- (2,3-Dihydro-1,4-benzodioxin-6-yl) -1,4-dihydroindeno[1,2-c]pyrazol-3-amine, inhibit, Hypoxia-inducible factors, Hypoxia, heterodimerization, HIF-1, HIF-PH, HIFs, HIF/HIF Prolyl-Hydroxylase, HeLa, HCT116, Inhibitor, ME23, GSCs, GN 44028, GN44028, GN-44028
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research
Purity
98.20% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.55 mM) ; DMSO:44 mg/mL (144.11 mM)
Smiles
C1c2ccccc2-c2[nH]nc (Nc3ccc4OCCOc4c3) c12
Molecular Formula
C18H15N3O2
Molecular Weight
305.33
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
E7505-1mgGN44028
A19693-200GN44028 200mg
A19693-1GN44028 1mg
A19693-10GN44028 10mg
A19693-5GN44028 5mg
A19693-100GN44028 100mg
A19693-50GN44028 50mg
A19693-25GN44028 25mg
A19693-10mM-DGN44028 10mM * 1mL in DMSO
bs-60325C-01GN44028 --- HIF-1α Inhibitor

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