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Deucravacitinib

CAT: 0013-GTR19175119-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175119-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Deucravacitinib (BMS-986165) is an oral, allosteric inhibitor that selectively targets the TYK2 pseudokinase (JH2) domain with high potency (IC50 = 1.0 nM) . It functions by stabilizing this regulatory domain, thereby blocking IL-12, IL-23, and type I interferon signaling pathways. This mechanism supports its research application in studying autoimmune disease models, both in vitro and in vivo.
CAS Number
1609392-27-9
Product Name Alternative
Deucravacitinib, BMS 986165, BMS986165, BMS-986165, IFNAR, Inhibitor, Interleukin Related, Interleukin, Interferon-α/β receptor, Interferon-alpha/beta receptor, Janus kinase, JAK1-JH2, JAK1 JH2, JAK, inhibit, Tyk2 JH2, TyrosineKinases, Tyrosine Kinases
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
>99.99% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.76 mM) ; DMSO:84.2 mg/mL (197.9 mM)
Smiles
[2H]C ([2H]) ([2H]) NC (=O) c1nnc (NC (=O) C2CC2) cc1Nc1cccc (-c2ncn (C) n2) c1OC
Molecular Formula
C20H19D3N8O3
Molecular Weight
425.46
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

Alternative Products

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B8781-50Deucravacitinib
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CS-O-65081Deucravacitinib-d6
HY-117287ADeucravacitinib (hydrochloride)
C13744-2mgDeucravacitinib (BMS-986165)
CS-EO-03258N-Nitroso Deucravacitinib
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RM-D223016-01Deucravacitinib Impurity 16
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