Products for Research Use Only

CGP60474

CAT: 0013-GTR19175029-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175029-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP60474 is a potent small molecule inhibitor targeting VEGFR-2 (IC50 = 84 nM), ATP-competitive PKC, and cyclin-dependent kinases (CDKs) . Its anti-endotoxemic activity makes it a valuable research tool for studying angiogenesis, cell cycle progression, and inflammatory responses in both cellular and animal models.
CAS Number
164658-13-3
Product Name Alternative
Inhibit, LPS, IL-6 level, Inhibitor, endotoxemic, ATP-competitive, CDK1/CyclinB, CDK2/CyclinE, CDK2/CyclinA, CDK, CDK4/CyclinD, CDK5/p25, CDK7/CyclinH, CGP60474, CGP-60474, CGP 60474, CDK9/cycT, Cyclin dependent kinase, survival, Protein kinase C, PKC, selective, VEGFR2, VEGFR-2
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.15% (May vary between batches)
Solubility
DMSO:117.5 mg/mL (330.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.62 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
OCCCNc1cc (ccn1) -c1ccnc (Nc2cccc (Cl) c2) n1
Molecular Formula
C18H18ClN5O
Molecular Weight
355.82
Storage Conditions
-20°C
Notes
For research use only.

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