Products for Research Use Only
RegisterLogin

CAY10526

CAT: 0013-GTR19174950-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19174950-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CAY10526 (BTH) is a selective microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor that suppresses the NF-κB signaling pathway. It is a valuable research tool for studying inflammation, pain, and cancer in both cellular and animal models, as evidenced by published in vitro and in vivo studies.
CAS Number
938069-71-7
Product Name Alternative
Cleaved caspase 3, CAY10526, CAY-10526, A375, BTH, CAY 10526, anti-apoptotic, microsomal PGE2 synthase-1, inhibit, increases apoptosis, increases BAX and BAK, mPGES1 inhibitor, mPGES-1, Inhibitor, melanoma xenografts, SB2, Prostaglandin Receptor, Prostaglandin E synthase, ProstaglandinReceptor, pro-apoptotic, PGE2 production, PGE synthase, WM793
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.75% (May vary between batches)
Solubility
Ethanol:1 mg/mL (3.21 mM) ;10% DMSO+90% Saline:1.5 mg/mL (4.82 mM) ; DMF:16 mg/mL (51.42 mM) ; DMSO:16 mg/mL (51.42 mM)
Smiles
OC1OC (=O) C (Br) =C1c1cc2ccccc2s1
Molecular Formula
C12H7BrO3S
Molecular Weight
311.15
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-(benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one
CAS Number938069-71-7
PubChem CID16220835
IUPAC Name3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one
Molecular FormulaC12H7BrO3S
Molecular Weight311.15
XLogP2.8
Topological Polar Surface Area74.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count17
Formal Charge0
Complexity382
SMILES
C1=CC=C2C(=C1)C=C(S2)C3=C(C(=O)OC3O)Br
InChI
InChI=1S/C12H7BrO3S/c13-10-9(11(14)16-12(10)15)8-5-6-3-1-2-4-7(6)17-8/h1-5,11,14H
InChIKey
ICCDILPNCJIDAW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one
CAS: 938069-71-7
CID: 16220835
Formula: C12H7BrO3S
MW: 311.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight311.15
XLogP32.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass309.92993
Monoisotopic Mass309.92993
Topological Polar Surface Area74.8 Ų
Heavy Atom Count17
Formal Charge0
Complexity382
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19190429CAY10506
GTR19175061-01CAY10566
GTR19192113-01CAY10726
GTR19156816-01CAY10566
GTR19191819-01CAY10722
GTR19191688-01CAY10565
GTR19191456-01CAY10727
GTR19191321-01CAY10486
GTR19190993-01CAY10503
GTR19190596-01CAY10766

Alternative Products

CatalogName
T23861-01CAY10526

Popular Products