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Tivozanib

CAT: 0013-GTR19174844-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174844-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tivozanib (KRN951) is an orally active small molecule inhibitor targeting VEGFR-1, -2, and -3. It exhibits potent antiangiogenic activity and is widely used in preclinical oncology research, including in vitro kinase assays and in vivo xenograft models for various solid tumors.
CAS Number
475108-18-0
Product Name Alternative
Angiogenesis, antitumor, AV 951, AV951, AV-951, Inhibitor, EphB2, Ephrin Receptor, EphrinReceptor, inhibit, KRN 951, KRN951, KRN-951, orally active, VEGFR2, VEGFR1, VEGFR, VEGFR3, vascular permeability, Vascular endothelial growth factor receptor, PDGFRα, Tivozanib, renal cell carcinoma
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.41% (May vary between batches)
Solubility
DMSO:38.33 mg/mL (84.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.4 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O (C=1C2=C (C=C (OC) C (OC) =C2) N=CC1) C3=CC (Cl) =C (NC (NC=4C=C (C) ON4) =O) C=C3
Molecular Formula
C22H19ClN4O5
Molecular Weight
454.86
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-10977-01Tivozanib

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