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PLX4720

CAT: 0013-GTR19174816-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174816-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLX-4720 is a selective ATP-competitive inhibitor of the oncogenic B-Raf V600E mutant, exhibiting an IC50 of 13 nM. It is widely used in cancer research to study MAPK pathway signaling and has demonstrated efficacy in both cellular assays and in vivo tumor models.
CAS Number
918505-84-7
Product Name Alternative
PLX4720, PLX-4720, PLX 4720, Inhibitor, inhibit, B-Raf, B-Raf (V600E), C-Raf-1 (Y340D/Y341D), Raf, Raf kinases
Field of Research
Signal Transduction
Purity
>98%
Bioactivity
Mutant B-Raf inhibitor
Form
Powder
Solubility
Soluble in DMSO (55 mg/ml with warming)
Smiles
CCCS (=O) (=O) Nc1ccc (F) c (C (=O) c2c[nH]c3ncc (Cl) cc23) c1F
Molecular Formula
C17H14ClF2N3O3S
Molecular Weight
413.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[3-[ (5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl) carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Alternative Products

CatalogName
202272PLX4720
TBI5113-25MGPLX4720, Mutant B-Raf inhibitor
P-8900PLX4720, Free Base [CAS# 918505-84-7]

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