Products for Research Use Only

MLi-2

CAT: 0013-GTR19174561-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19174561-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MLi-2 is a brain-penetrant, highly selective LRRK2 kinase inhibitor with sub-nanomolar potency in biochemical, cellular binding, and phospho-Ser935 dephosphorylation assays. This tool compound is widely used in Parkinson's disease research for investigating LRRK2 biology and pathogenesis in both in vitro and in vivo models.
CAS Number
1627091-47-7
Product Name Alternative
Disease, Leucine-rich repeat kinase 2, Parkinson's, LRRK2, orally, MLi 2, MLi2, MLi-2, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
98.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM) ; DMSO:60 mg/mL (158.12 mM)
Smiles
C[C@H]1CN (C[C@@H] (C) O1) c1cc (ncn1) -c1n[nH]c2ccc (OC3 (C) CC3) cc12
Molecular Formula
C21H25N5O2
Molecular Weight
379.46
Storage Conditions
-20°C
Notes
For research use only.