Products for Research Use Only

MT-802

CAT: 0013-GTR19175457-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175457-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MT-802 is a potent PROTAC-based BTK degrader with a DC50 of 1 nM. It is a research tool for investigating Bruton's tyrosine kinase (BTK) biology and has shown potential in preclinical studies targeting C481S mutant chronic lymphocytic leukemia (CLL) in cellular models.
CAS Number
2231744-29-7
Product Name Alternative
Inhibit, MT802, MT-802, MT 802, Inhibitor, Bruton tyrosine kinase, Btk, BTK, PROTAC, PROTACs
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.93% (May vary between batches)
Solubility
DMSO:135 mg/mL (171.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.08 mM)
Smiles
NC1=C2C (=NN (C2=NC=N1) C3CCN (CCOCCOCC (NC=4C=C5C (=CC4) C (=O) N (C5=O) C6C (=O) NC (=O) CC6) =O) CC3) C7=CC=C (OC8=CC=CC=C8) C=C7
Molecular Formula
C41H41N9O8
Molecular Weight
787.82
Storage Conditions
-20°C
Notes
For research use only.