Products for Research Use Only

Ogerin

CAT: 0013-GTR19174724-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174724-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ogerin is a selective positive allosteric modulator of GPR68 (pEC50 6.83) that has been shown to inhibit fear memory recall in mouse models. It also exhibits inverse agonist/antagonist activity at the adenosine A2A receptor (Ki 220 nM) and weak antagonist activity at the serotonin 5-HT2B receptor (Ki 736 nM) . This profile makes it a useful research tool for studying neuropsychiatric conditions and GPCR signaling in both in vivo and in vitro experiments.
CAS Number
1309198-71-7
Product Name Alternative
Inhibitor, inhibit, Ogerin, HEK293, GPR68, fibrotic diseases, G Protein-Coupled Receptor 68, fibroblasts, 5HTReceptor, 5HT Receptor, A2A, A2A receptoor, 5-HT2B receptor, 5-HT2B, AdenosineReceptor, Adenosine Receptor, TGF-β
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.50% (May vary between batches)
Solubility
DMSO:250 mg/mL (813.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (16.27 mM)
Smiles
Nc1nc (NCc2ccccc2) nc (n1) -c1ccccc1CO
Molecular Formula
C17H17N5O
Molecular Weight
307.35
Storage Conditions
-20°C
Notes
For research use only.

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