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GSK2838232

CAT: 0013-GTR19174475-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174475-05Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK2838232 is a novel small molecule HIV-1 maturation inhibitor that also demonstrates inhibitory activity against HIV reverse transcriptase across diverse viral isolates. It is utilized in research to study antiviral mechanisms and has been evaluated in both in vitro assays and in vivo preclinical models of HIV infection.
CAS Number
1443460-91-0
Product Name Alternative
Inhibit, Inhibitor, HIV Protease, HIVProtease, HIV, GSK2838232, GSK-2838232, GSK 2838232, Human immunodeficiency virus
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
97.97% (May vary between batches)
Solubility
DMSO:50 mg/mL (61.76 mM)
Smiles
[H][C@]12CC[C@]3 ([H]) [C@@]4 (C) CC[C@H] (OC (=O) CC (C) (C) C (O) =O) C (C) (C) [C@]4 ([H]) CC[C@@]3 (C) [C@]1 (C) CC[C@]1 (CC (=O) C (C (C) C) =C21) [C@@H] (O) CN (CCN (C) C) Cc1ccc (Cl) cc1
Molecular Formula
C48H73ClN2O6
Molecular Weight
809.56
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Gsk-2838232

second generation HIV maturation inhibitor

CAS Number1443460-91-0
PubChem CID71580991
IUPAC Name4-[[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[(1R)-2-[(4-chlorophenyl)methyl-[2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3H-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid
Molecular FormulaC48H73ClN2O6
Molecular Weight809.6
XLogP7.2
Topological Polar Surface Area107
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count14
Heavy Atom Count57
Formal Charge0
Complexity1560
SMILES
CC(C)C1=C2[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC[C@]2(CC1=O)[C@H](CN(CCN(C)C)CC6=CC=C(C=C6)Cl)O)C)C)(C)C)OC(=O)CC(C)(C)C(=O)O)C
InChI
InChI=1S/C48H73ClN2O6/c1-30(2)40-34(52)26-48(37(53)29-51(25-24-50(10)11)28-31-12-14-32(49)15-13-31)23-22-46(8)33(41(40)48)16-17-36-45(7)20-19-38(57-39(54)27-43(3,4)42(55)56)44(5,6)35(45)18-21-47(36,46)9/h12-15,30,33,35-38,53H,16-29H2,1-11H3,(H,55,56)/t33-,35+,36-,37+,38+,45+,46-,47-,48+/m1/s1
InChIKey
MEOWKUXNVNJAMY-PZFKGGKESA-N
Chemical Structure
2D Structure
2D structure of Gsk-2838232
CAS: 1443460-91-0
CID: 71580991
Formula: C48H73ClN2O6
MW: 809.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight809.6
XLogP37.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count14
Exact Mass808.5157157
Monoisotopic Mass808.5157157
Topological Polar Surface Area107 Ų
Heavy Atom Count57
Formal Charge0
Complexity1560
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B5818-10GSK2838232
A15965-50GSK2838232 50mg
A15965-10GSK2838232 10mg
A15965-5GSK2838232 5mg

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