Products for Research Use Only

LUT014

CAT: 0013-GTR19174332-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174332-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LUT014 is a potent B-Raf inhibitor (IC50: 11.7 nM) developed to mitigate EGFR inhibitor-induced acneiform lesions. It is a research tool for studying targeted therapy combinations and resistance mechanisms in oncology, applicable in both in vitro and in vivo models of skin toxicity and cancer.
CAS Number
2274819-46-2
Product Name Alternative
Inhibitor, LUT 014, LUT014, LUT-014, inhibit, B-Raf, Raf kinases, Raf
Field of Research
Signal Transduction
Purity
96.34% (May vary between batches)
Solubility
DMSO:50 mg/mL (94.61 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.78 mM)
Smiles
Cc1ccc2c (Nc3cccc (OC (F) (F) F) c3) nccc2c1Nc1ncccc1-c1ncnc2[nH]cnc12
Molecular Formula
C27H19F3N8O
Molecular Weight
528.49
Storage Conditions
-20°C
Notes
For research use only.