Tenoxicam

Chemical Information
Tenoxicam is a thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. It is a member of pyridines, a monocarboxylic acid amide, a thienothiazine and a heteroaryl hydroxy compound.
| CAS Number | 59804-37-4 |
| PubChem CID | 54677971 |
| IUPAC Name | 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide |
| Molecular Formula | C13H11N3O4S2 |
| Molecular Weight | 337.4 |
| XLogP | 1.1 |
| Topological Polar Surface Area | 136 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 599 |
| Property | Value |
|---|---|
| Molecular Weight | 337.4 |
| XLogP3 | 1.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 337.01909819 |
| Monoisotopic Mass | 337.01909819 |
| Topological Polar Surface Area | 136 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 599 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
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