Ferritin, Light Chain (FTL) (Microglia Marker)

• Gene Name:

  [FTL]

• NCBI Gene ID:

  2512

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

• Other Gene Names:

  [FTL; FTL; LFTD; NBIA3; Ferritin L subunit]

• Short Name:

  [Ferritin, Light Chain (FTL)]

• Other Product Names:

  [ferritin light chain; Ferritin light chain; ferritin light chain; ferritin light chain]

• NCBI GI Number:

  20149498

• NCBI Accession Number:

  NP_000137.2

• NCBI GB Accession Number:

  NM_000146.3

• Uniprot Accession Number:

  P02792