MUC1 / EMA /CD227 (Epithelial Marker) Mouse Monoclonal Antibody

• Gene Name:

  [MUC1]

• NCBI Gene ID:

  4582

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

• Other Gene Names:

  [MUC1; MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta]

• Short Name:

  [MUC1 / EMA /CD227]

• Other Product Names:

  [mucin-1 isoform 2; Mucin-1; mucin-1; mucin 1, cell surface associated; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3]

• NCBI GI Number:

  67189007

• NCBI Accession Number:

  NP_001018016.1

• NCBI GB Accession Number:

  NM_001018016.2

• Uniprot Accession Number:

  P15941

• CAS Number:

  9007-83-4