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FR 122047

CAT: 0013-GTR19174047-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174047-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FR 122047 hydrochloride is a potent and selective cyclooxygenase-1 (COX-1) inhibitor, exhibiting an IC50 of 28 nM for human recombinant COX-1 versus 65 μM for COX-2. This small molecule is a valuable research tool for investigating COX-1-specific roles in physiological and pathophysiological processes, including platelet aggregation and gastric function, in both in vitro and ex vivo experimental models.
CAS Number
130717-51-0
Product Name Alternative
Inhibitor, FR 122047, FR 122047 hydrochloride, FR122047, FR-122047, inhibit, 4,5-Bis (4-methoxyphenyl-2-[ (1-methylpiperazin-4-yl) carbonyl]thiazole, Hydrochloride, 1-[ (4,5-Bis (4-methoxyphenyl-2-thiazoyl) carbonyl]-4-methylpiperazine, Hydrochloride, COX, COX-2, COX-1, Cyclooxygenase
Field of Research
Immunology & Inflammation, Neuroscience
Purity
99.63% (May vary between batches)
Solubility
DMSO:4 mg/mL (8.7 mM) ; H2O:2 mg/mL (4.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.17 mM)
Smiles
CN1CCN (CC1) C (=O) C2=NC (=C (S2) C3=CC=C (C=C3) OC) C4=CC=C (C=C4) OC.Cl
Molecular Formula
C23H26ClN3O3S
Molecular Weight
459.99
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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BUP03875-01FR 122047
1507/10FR 122047 hydrochloride
407335FR-122047 HCl

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