c-Myc Oncoprotein Mouse Monoclonal Antibody

• CAS Number:

  9007-83-4

• Gene Name:

  [MYC]

• NCBI Gene ID:

  4609

• Reactivity:

  Human.
  Others not tested

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCLs) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential of the lymphomas.

• Other Gene Names:

  [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39]

• Short Name:

  [c-Myc Oncoprotein]

• Other Product Names:

  [myc proto-oncogene protein; Myc proto-oncogene protein; myc proto-oncogene protein; v-myc avian myelocytomatosis viral oncogene homolog; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64]

• NCBI GI Number:

  71774083

• NCBI Accession Number:

  NP_002458.2

• NCBI GB Accession Number:

  NM_002467.4

• Uniprot Accession Number:

  P01106